Iron Plays a Certain Role in Patterned Hair Loss PMC

Table Of Content

• Diet changes
• What are the benefits of iron supplements and what are they used for?
• Supplements
• Does Collagen Support Hair Growth?
• Symptoms of Iron Deficiency Anemia
• Vitamin A
• Replacing Iron Levels

To prevent iron deficiency anemia in infants, feed your baby breast milk or iron-fortified formula for the first year. Cow's milk isn't a good source of iron for babies and isn't recommended for infants under 1 year. After age 6 months, start feeding your baby iron-fortified cereals or pureed meats at least twice a day to boost iron intake.

Diet changes

If this indicates a deficiency, it’s worth going to your GP for a full blood count which includes haemoglobin and other red blood cell measurements. This study owns its value because it demonstrates the first direct comparison between hair loss patients and same number of healthy controls matched by age and sex. It strongly supports the previous studies that ID can be a certain factor of developing or worsening FPHL especially in premenopausal female patients. However, screening for ID as the first evaluation of hair loss in even male patients might be worthwhile in the clinical field. The recommended dietary allowance for selenium is 55 μg daily for individuals aged ≥ 14 years in U.S. populations. The availability of selenium in a variety of foods, such as meat, vegetables, and nuts, are sufficient to meet the daily requirement [120].

What are the benefits of iron supplements and what are they used for?

That might sound positive for your hair, but consuming too much vitamin A can actually cause hair loss. Vitamin E helps support your immune system and other bodily functions. Hair loss and hair shedding can be a symptom of biotin deficiency.

Supplements

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Additionally, lifestyle changes and stress management can help mitigate hair loss symptoms,' says Dr. Balwi. To elucidate the role of vitamin D in FPHL and TE, additional large-scale trials are necessary [77]. Management of alopecia is an essential aspect of clinical dermatology given the prevalence of hair loss and its significant impact on patients’ quality of life. Androgenetic alopecia (AGA), telogen effluvium (TE), and alopecia areata (AA) represent the three most common types of non-scarring alopecia [9]. There are several reasons to suspect a role for micronutrients in non-scarring alopecia. If you are eating a well-balanced diet, your body should be getting all the nutrients it needs, so you probably don’t need to take additional vitamins.

When the body does not have enough iron, it cannot produce enough haemoglobin, leading to a decrease in the number of red blood cells. Studies on the role of iron in AA have shown a discrepancy in the results between females and males. There is a need for placebo-controlled clinical trials evaluating iron supplementation in the treatment of AA. Most studies on zinc have revealed lower serum levels in AA patients than in controls. Biotin deficiency causes hair loss, but there are no evidence-based data that supplementing biotin promotes hair growth. Moreover, exogenous biotin interferes with some laboratory tests, creating false negative or false positive results.

This is promising for regrowth because it means that the follicles are not severely damaged and may be able to grow hair again. ‘Telogen effluvium is a type of hair loss resulting from the disruption of the hair growth phase. When more hairs are in the resting phase than in the growing phase, extensive hair shedding and sudden hair loss in women can occur. A 2022 study on in vitro (out of the body, typically using test tubes and similar equipment) human dermal papilla cells and mice found some potential positive effects from fish-derived collagen peptides. These findings suggest that fish-derived collagen peptides could, at some point, be used to promote hair growth, but more research is needed on humans to confirm this finding. Iron supplements can be particularly important for women and pregnant women, babies and young children.

Vitamin A

If your levels are very low, a doctor may recommend iron supplements. In some cases, you may need treatment for an underlying condition. There are many causes of hair loss in both women and men, so if you’re concerned about it, your first step should be booking an appointment with a doctor to discuss your options.

Replacing Iron Levels

Sometimes, hair loss can be caused by getting too much of a certain vitamin or mineral. Continue reading to learn more about which vitamin deficiency causes hair loss, hair loss causes, and how to stop hair loss. There is no evidence that any one type of iron salt, liquid, or pill is better than the others, and the amount of elemental iron varies with different preparations.

Gentle traction yielded four to five hairs, all of which were in the telogen phase. One month after termination of vitamin A supplementation, hair loss was no longer a problem. The authors concluded that signs of hypervitaminosis A were misinterpreted as symptoms of chronic renal failure. The authors also highlighted the possible “insidious” effects of exogenous vitamin A on dialysis patients [20]. If you’re deficient in iron, that means your hemoglobin levels are low. Without enough hemoglobin, the hair follicle stem cells lack the oxygen necessary to stimulate hair growth, which can result in male-pattern baldness in men and female-pattern baldness in women.

Selenium ingestion in an amount exceeding 400 μg daily may cause toxicity. Symptoms of acute or chronic selenium toxicity include nausea, vomiting, nail brittleness and discolorations, hair loss, fatigability, irritability, and foul breath odor [120]. An outbreak of selenium toxicity from a liquid dietary supplement that contained 200-fold the labeled concentration of selenium resulted in severe hair loss in most patients [121]. Venton et al. described the loss of pigmentation of the hair in four patients receiving TPN without selenium supplementation.

These treatments that emit red- or near-infrared light are believed to stimulate hair follicles to help hair grow, with a lower risk of side effects compared to topical creams and oral medications. Doctors often prescribe oral medications to be used along with topical minoxidil because studies show the combination boosts hair production. Low-dose oral minoxidil (prescribed off-label) has been found to be effective and safe for most patients, Mirmirani says. Other oft-used drugs include finasteride (Propecia) and spironolactone.

Children and older adults share symptoms, but neurological symptoms, like ADHD, are more common in children. In the later stages of iron deficiency, the nails can become spoon-shaped, meaning that the middle of your nail dips and the edges raise to give a rounded appearance like a spoon. Spoon-shaped fingernails, also called koilonychia, are another symptom of iron deficiency anemia. People with iron deficiency anemia may have restless legs syndrome, which is a strong urge to move your legs while at rest. Consequently, iron deficiency may worsen conditions that affect your heart, such as heart failure and coronary heart disease. Since tiredness is often considered a part of a busy, modern life, it’s difficult to diagnose an iron deficiency based on this symptom alone.

It’s usually genetic, but it can also be triggered by diseases or disorders that attack the hair follicles. In pregnancy, iron deficiency anaemia is most often caused by a lack of iron in your diet. Your GP may carry out repeat blood tests over the next few months to check that your iron level is getting back to normal.

Taken together, these changes were concurrent with drug toxicity that aligned with the patient’s over-consumption of vitamin A [21]. AnemoCheck is the first-ever smartphone app that provides instant hemoglobin estimation with just a fingernail selfie—no appointments and no needles necessary. As you make diet and lifestyle changes to increase your iron levels, you can use our app to track how it affects your hemoglobin.

Indeed, people with iron deficiency anemia are six times more likely to have restless leg syndrome than the general population. A sore, swollen, or strangely smooth tongue may be a sign of iron deficiency anemia, as are cracks on the corners of your mouth. In cases of iron deficiency, your heart has to work especially hard to transport oxygen.

But if you don’t have a confirmed biotin deficiency, taking biotin supplements won’t help with hair loss. That’s surprising to many people since many companies sell shampoos and other products with biotin, claiming that they’ll improve hair health. Researchers have called for more double-blind placebo studies to examine the role of vitamin and mineral intake on hair loss.

Iron deficiency anaemia

Table Of Content

• What Are the Signs and Symptoms of Iron-Deficiency Anemia?
• Choose foods containing vitamin C to enhance iron absorption
• Harvard Health Ad Watch: New drug, old song, clever tagline
• How we reviewed this article

Having low ferritin interferes with your body’s role in making red blood cells. Red blood cells are important for the transfer of oxygen throughout your body. Without enough red blood cells, your organs and major systems don’t work as effectively.

What Are the Signs and Symptoms of Iron-Deficiency Anemia?

Your doctor can help you change your diet to get the right amount of iron for your needs. There is no clear-cut evidence in the existing medical literature of an association between iron deficiency and nonscarring alopecia. Iron supplements commonly cause constipation, so slow-release supplements are preferred. It’s important to talk to your doctor first, before taking iron supplements, though.

Choose foods containing vitamin C to enhance iron absorption

Beyond what you put into your body, keeping good hair hygiene may also help with some forms of hair loss. Avoid using harsh chemicals on your hair, and don’t be too rough on it while brushing. Use straighteners and hair curlers that emit a lot of heat sparingly. With a combo of this and an iron-rich diet, you’ll be on your way to healthier hair. For men and postmenopausal women, gastrointestinal blood loss (which can occur from conditions like ulcers, Crohn’s disease, and celiac disease) is a leading cause of low iron. People living with kidney failure or who practice a vegan diet may also be more prone to iron deficiencies.

Harvard Health Ad Watch: New drug, old song, clever tagline

By contrast, scarring alopecia, another autoimmune disease that causes hair loss, is often accompanied by itchiness, tenderness and scaling of the scalp. Scarring alopecia is the most devastating type of hair loss, Mirmirani says, because it permanently destroys the hair follicles. In this study, patients with MPHL show relatively early onset age, which means they appear to visit the clinic earlier than those with FPHL. Patients with FPHL show definitely lower serum FC compared with age/sex-matched normal controls.

Normal or heavy menstrual bleeding can lead to iron deficiency anemia. You can develop iron deficiency if you don't eat enough iron-containing foods or if you have trouble absorbing iron. Vegetarians and vegans may be more prone to iron deficiency, especially premenopausal females. This is because non-heme iron, the form found in plants, is not absorbed as well as heme iron, the form found in meat, poultry, and fish. The results of an adapted Newcastle-Ottawa scale for the risk of bias assessment of the included studies are shown in online supplementary Table 1 and 2. Of 21 case-control studies, 14 were of good quality (7–8/9), 7 were of fair quality (5–6/9), and none was of poor quality.

A cutoff of 30 µg/L yields a sensitivity of 92% and a specificity of 98%, while a cutoff of 41 µg/L yields a sensitivity of 98% and a specificity of 98%. It might have contributed to the controversy that there is no guideline to define ID. From this study, over 80% of FPHL showed serum FC lower than 70 µg/L, while only less than 20% of age matched healthy female controls showed it. No female healthy controls showed serum FC lower than 30 µg/L in this study. Therefore, serum FC lower than 30 µg/L might be a clinically significant indicator for ID especially in female hair loss patients considering their menstrual status.

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In some cases, iron deficiency anemia can develop and result in low blood pressure, heart palpitations, shortness of breath, and an increased risk for infections. The best way to treat hair loss is to address the underlying cause of the problem. If you think your hair loss is related to an iron deficiency, consult a doctor to measure your iron levels. Your doctor will most likely order a ferritin level blood test, which measures the levels of a protein called ferritin that helps store iron. Folate is another water-soluble B vitamin and includes naturally occurring food folate and folic acid (fully oxidized monoglutamate).

Among participants experiencing excessive hair loss or shedding, roughly 10% more had low iron stores compared to the remainder of the population (Deloche, 2007). While the science looks promising, further studies are needed to prove a link between iron deficiency and hair loss. Iron deficiency causes a type of anemia, which is when there aren’t enough healthy red blood cells to deliver enriching oxygen to the rest of the body.

Women with heavy periods can become low in iron because they lose blood during their cycle. Heavy periods mean losing blood over a longer period, which can reduce your storage of iron. This iron loss also happens if you have endometriosis, a condition where tissue grows outside of the uterus and can cause heavy bleeding during your period. Unfortunately, it can be easy to overlook ferritin if you also have an underlying condition that may cause hair loss.

Hypervitaminosis A causes hair loss, and data on the effects of isotretinoin in hair loss support this association. Published data on AA suggest that vitamin D, due to its immunomodulatory effect, may be involved in AA [66, 67]. Lee et al. conducted a systematic review and meta-analysis of observational studies on the prevalence of vitamin D deficiency and/or serum vitamin D levels and AA [68]. These authors analyzed a total of 14 studies that involved 1255 patients with AA and 784 control patients without AA. The mean serum 25-hydroxyvitamin D [25(OH)D] level in patients with AA was significantly lower than that in the non-AA control group, by 8.52 ng/dL (95% confidence interval − 11.53 to − 5.50 ng/dL). Vitamin D deficiency was also highly prevalent in patients with AA, leading the authors to suggest that the vitamin D level has to be measured in patients with AA.

If a person suspects their iron levels may be low, they should visit a doctor who can perform blood tests to determine if they are anemic. While hair loss is not a typical symptom of iron deficiency anemia, some people might experience it. ‘Traction alopecia is hair loss caused by repeated pulling or tension on the hair follicles. Tight hairstyles like braids, weaves, or ponytails are common culprits. For many women, hair shedding is a normal and common occurrence with the NHS highlighting that we can lose between 50 and 100 hairs a day, often without noticing.

Gastric bypass, for example, often involves the removal of sections of the stomach or intestine. All data generated or analyzed during this study are included in this article and its online supplementary material files. While iron deficiencies can cause hair loss, so can several other factors. Let's look at those to better understand what can cause thinning hair. Topical products containing collagen, such as skin creams and serums, are available, but research backing their efficacy is lacking. Collagen is found in deeper layers, but collagen fibers are too large to permeate the outer skin layers, and peptides (shorter chains of collagen) are unsuccessful.

35 Blonde Highlights on Brown Hair Color Ideas

Table Of Content

• Wavy Brown Hair with Blonde Highlights
• #2 Dark Brown Hair with Blonde Highlights and Lowlights
• Light Brown Hair With Blonde Highlights
• Dark Chestnut Brown with Caramel Blonde Highlights
• #33: Lovely Rich Brown Hair with Silver Streaks

A blended burgundy/violet balayage with a deep brown looks spectacular. Adding some teasylights (teased foil highlights) through the top helps to break up what could otherwise be a harsh base color. The best thing about this brown style of balayage makes a very bold violet-red look much more natural and approachable.

Wavy Brown Hair with Blonde Highlights

It’s always best to start slowly to maintain your hair’s integrity. It requires time, patience, and quite an investment in your appointments and home hair care. Go for a gorgeous long side-swept hairstyle with brown hair highlights.

#2 Dark Brown Hair with Blonde Highlights and Lowlights

Plus, the contrast and radiance created by opposing dark and light tones are beautifully intertwined into your strands! With a combined blonde and dark brown hair color, you’ll be free to style your locks however you want and still get a voguish result. Imagine wearing these honey blonde highlights on your dark hair. This hair color makes a modern, playful finish when paired with beachy waves.

Light Brown Hair With Blonde Highlights

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If you have warm-toned skin, this color blend will look great on you. Partial highlights are highlights that are done only on the top layer of hair. This is a great way to try highlights if it is your first time. The blend of platinum and champagne partial highlights goes well with walnut brown hair. These highlights add texture to your hair and make it look voluminous.

This edgy bob with dark roots and blonde highlights makes a bold statement. It’s a fresh take on classic style, offering a striking contrast that’s sure to turn heads and suit those with a round or oval face shape to perfection. This chic pixie cut, adorned with platinum highlights, offers a daring and high-contrast look that’s both bold and beautiful. The darker roots add depth, while the platinum pieces create a sense of texture and movement.

Pair these highlights with light brown highlights to add oodles of dimension and texture to your brown locks. According to our experts, there are four main benefits of getting blonde highlights on brown hair. For starters, highlights can add dimension and depth to your natural hue. And depending on the shade and placement of your highlights, they can also create a sun-kissed appearance.

Ask your stylist if they have any ideas to make your color pop. If you’re into chocolates, then this style will look delectable! The fair amber highlights mixed with the dark chocolate brown hair almost mimic a bite of a mocha truffle.

Caramel Face-Frame

If you're afraid of your highlights turning brassy, consider asking your colorist for cool brunette highlights. Ashy in tone, you won't have to worry about any orange tones popping through. If you don't want to shy away from a lighter mane, make sure to go for a rooted look. This rooted ice blonde color is sure to create some serious, envy-worthy contrast. For those who want an all-over lighter mane, ask your colorist for an off-the-root or rooted highlight.

#33: Lovely Rich Brown Hair with Silver Streaks

Her light brown hair with subtle blonde highlights, paired with her green eyes, is the perfect balance of Earth tones. With enough blonde highlights on lighter brown hair, it makes a sun-kissed dimension. For a low-maintenance finish, ask the stylist for dark roots. Medium brown hair with blonde highlights for women over 60 offers a youthful vibe.

Remember to leave some hairs out to create a much more ‘careless’ look. This is an impressive balayage you definitely want to copy. Maham is a seasoned beauty & lifestyle writer with a master’s degree in agricultural science. She loves to research latest hairstyle & hair color trends and isn't afraid to try out the newest hairstyles. Layers are hard to make noticeable in dark hair, so it’s hard to get that theatrical side-swept look that many celebrities sport on a daily basis. However, highlights can fix this issue, especially if they’re concentrated on the layers as seen in this example.

If you’re a brunette, spice your color with a few different natural tones. You can keep your hair looking healthy with hair treatments such as Olaplex. This keeps your subtle caramel highlights and other hues looking amazing and protects your hair from damage and breakage. If you have naturally very dark or deep brown hair color, ask for a combination of foilayage and babylight.

If you’re currently rocking a full fringe, consider adding this light brown shade for warmth. Similar to Margot Robbie, this small change can also bring out your eye color (in this case, her baby blues) and provide a soft contrast to your natural shade. In contrast to caramel bronde, this variation takes a subtler approach. The light shade starts at the mid-length section of your hair before descending into a darker brown at the ends. To recreate Niecy Nash’s cascading color, a stylist will focus on each section at a time, so everything blends together beautifully. If you don’t want to end up with damaged unevenly painted hair, just leave it all up to a professional when it comes to highlights.

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If you want a look that has a lot of depth and texture, this pretty balayage is calling your name! Ask for long layers to add some volume to your hair as well. Yes, color-depositing shampoos can work on natural and dyed hair. However, you must use the right tone for your hair, says O’Connor.

Truly, the different tones and colors mix together well, which will creat an ultra-chic dimension in your hair. Try a brown-blonde gradient ombre hair color if you want a beautiful low-maintenance hue. The seamless transition from brown to blonde will have people obsessed!

That’s why we suggest you let autumn inspire you and borrow some of the lovely colors of falling leaves. However, the difference lies in the shade of blonde that you use. This one is a deeper tone of nutmeg mixed with a bit of chestnut. We’re not done with wavy locks because here is an incredibly easy and sweet haircut that revolves around the mermaid look. There are highlights & lowlights, and there’s ombre, and then there’s balayage. This coloring job is so well done that you can barely notice that highlights were applied in the first place.

It’s best to style your tresses with waves to avoid a flat finish when wearing shades like this. Hair color like this looks more promising when shiny, so use oil for added glow. Get your hair to sparkle with honey beige bronde hair with partial highlights. When you highlight your medium brown hair, you can achieve warm honey-rich highlights easily.

47+ Flattering Brown Hair with Blonde Highlights to Inspire Your Next Hairstyle

Table Of Content

• Caramel Tone with Blonde Highlights
• Dark Blonde Highlights
• #37: Lived-In Caramel And Blonde Highlights in Brown Hair
• Midnight Brown with Platinum Highlights

Lastly, they’re a low-maintenance option that won’t make regrowth too noticeable. As Lopez previously explained, “This hair color is a caramel brunette mixed with milky blonde. Bronde is a staple shade, especially if you want to add blonde highlights on brown hair.

Caramel Tone with Blonde Highlights

Stylist Thalia mixes brown and blonde hues with textured hair that breathes life into the curls. This has a chestnut brown base and both the lowlights and highlights here are a very beautiful neutral pale blonde. This latter is a process through which both highlights and lowlights are added to darker hair so as to make it look a lot more natural. Do you want to do “something” with your hair, a change that is not radical but that makes you feel good? A few highlights lighter than your base shade will give you a fresh look.

Dark Blonde Highlights

Starting with a medium cool brown and ending in a perfect buttery blonde, these tresses almost drip with gold. The goal of this look is to make everything mold together seamlessly for a rich finished color. The pure chocolate brown is matched with a neutral beige blonde for a unified palette. With her hair chameleon tendencies, it should be of no surprise that Zendaya made our list twice. If anyone can pull off a bowl cut with caramel balayage, it's Zendaya. This tousled, layered look feels chic and a bit edgy, and we absolutely love it.

#37: Lived-In Caramel And Blonde Highlights in Brown Hair

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But remember that it releases the color just as fast do uneven porosity levels. Pay attention to how much better your color holds after continued treatment use. Beige highlights are a great option for a brunette trying out highlights for the first time. If you are considering dyeing your hair, consult a professional on what shade of highlight will work best with your skin tone. If you wear your hair up, ask for a full highlight so you can see the highlights in the back with your hair up. If you want more low maintenance, you can ask for your root to be shadowed back to erase any lines.

Short Bob Hairstyle with Fiery Blonde Highlights

Beige blonde highlights add sparkles to a dark brunette hair color. Beige blonde is ideal if you have a warmer skin complexion, too. A classic blonde balayage like this isn’t complete without the waves.

Golden brown and blonde highlights for older women are the perfect choice for women wanting to spice things up. Tapping the root with a gloss will also make the grow-out more seamless. Show off your multi-dimensional color with the perfect blowout style. Beautiful loose waves display warm, inviting blonde and brown tones. Use a curling iron to get glamorous Hollywood waves and be ready to take on the day. If you like cool vibes with your hair, brown hair with white ash highlights is a great pick.

It's hard to go wrong with sandy brown hair, unless you're leaving it flat in color. Inject some personality into the beige tone with blonde highlights that complement the neutral natural color. This light brown lob gets an icy touch with platinum blonde highlighting from roots to ends.

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Ladies, go for it if you have been waiting to add fun, vibrant colors to your locks. The contrasting colors give off a multi-dimensional tone and add depth to your hair. Glistening warm highlights give your hair a delicious shine.

If you’re a brunette thinking of going blonde, opt for a dirty blonde balayage. It’ll show you how you’ll look as a blonde without the commitment of bleaching all your hair. Heavy blonde highlights can add tons of texture to your hair.

Darker brown hair with blonde highlights is a gorgeous bombshell combination. We’re back to ideas on what type of blonde you could wear as part of your brown hair with blonde highlights. The name speaks for itself when it comes to this example of brown hair with blonde highlights. Now you can braid your brown hair with blonde highlights in a romantic French crown braid. Since we saw what brass could do to brown and blonde hair, let’s take a look at copper.

Brown hair with blonde highlights is a hair lightening technique that paints blonde on strands of a brown base. Adding pretty shades of blonde highlights lightens medium to dark brown hair and creates more dimension and depth. “Warm caramel blonde highlights that seamlessly blend with brown hair creates a rich honey appearance,” says Haliti.

Feel free to take screenshots for your next salon appointment. This is yet another example of the contrast you can achieve by placing platinum or silver highlights on dark brown hair. Well-blended highlights will make it seem as if you have solid but very shiny hair color. You should choose this option if you want to add some shimmer to your light brown locks. If your hair is naturally dark brown, you can try out dark blonde streaks for a more natural look. You can also add platinum or silver highlights to the mix as well.

It’s particularly flattering for oval and heart-shaped faces, as the light ends can soften strong jawlines while the dark roots draw attention upward. The voluminous curls are elegantly elevated with cascading blonde highlights that flow like liquid gold. This style is a testament to the timeless beauty of well-placed highlights, which can transform a simple curl into a glamorous wave.